Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29708869 | 0.91 | USP30 (0.32) | USP30GSTO1 | |
| SCHEMBL29235853 | 0.91 | ALDH1A1 (0.32) | USP30GSTO1HRH3 | |
| SCHEMBL29235625 | 0.84 | HRH3 (0.30) | GSTO1HRH3 | |
| SCHEMBL29598733 | 0.72 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL29598635 | 0.72 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL29235800 | 0.70 | GSTO1 (0.40) | GSTO1 | |
| SCHEMBL29708400 | 0.70 | ALDH1A1 (0.33) | GSTO1 | |
| SCHEMBL8367145 | 0.70 | CA2 (0.39) | USP30FPR2SCN9A | |
| SCHEMBL29235538 | 0.70 | HRH3 (0.34) | HRH3 | |
| SCHEMBL29708663 | 0.69 | ALDH1A1 (0.33) | GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003988-A1 | 3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS | Les Laboratoires Servier (FR) | 2022-06-01 | — | — | EP | disclosed |