Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tranexamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG known ✓ | P00747 | 1/20 | 0.95 |
| ▸ | PLAT | P00750 | 1/20 | 0.95 |
| ▸ | LMNA | P02545 | 1/20 | 0.95 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tranexamic Acid SCHEMBL29236546 | 1.00 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL423790 | 0.98 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL322487 | 0.98 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL16974 | 0.98 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL186034 | 0.98 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL349408 | 0.98 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL11189660 | 0.95 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL3793503 | 0.95 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL7323218 | 0.95 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL10723480 | 0.95 | PLG (0.95) | PLGPLATLMNAANPEPENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184537-A | Preparation method of high-purity Sha Kuba valsartan sodium | 浙江普洛家园药业有限公司 | 2024-06-14 | — | — | CN | disclosed |