Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tranexamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG known ✓ | P00747 | 1/20 | 1.00 |
| ▸ | PLAT | P00750 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | ANPEP | P15144 | 1/20 | 0.52 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tranexamic Acid SCHEMBL16974 | 1.00 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL423790 | 1.00 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL186034 | 1.00 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL322487 | 1.00 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL19031783 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL3793503 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL11189660 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL10723480 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL7326280 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL29236634 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 513 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346589-A1 | RADIOISOTOPE LABELED SSTR2-AGONISTS WITH LINKERS | UNIV ERASMUS MED CT ROTTERDAM (NL) | 2025-11-13 | — | — | US | claimed |
| WO-2025095745-A1 | VASCULARIZATION SYSTEM FOR TRANSPLANTATION OF ENDOCRINE ORGANOIDS | 서울대학교산학협력단 | 2025-05-08 | — | — | WO | claimed |
| EP-4529474-A1 | RADIOISOTOPE LABELED SSTR2-AGONISTS WITH LINKERS | Erasmus University Rotterdam Medical Center (NL) | 2025-04-02 | — | — | EP | claimed |
| WO-2024063648-A1 | Platform and scaffold for FAP targeting agents | ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM (NL) | 2024-03-28 | — | — | WO | claimed |
| EP-4342890-A1 | PLATFORM AND SCAFFOLD FOR FAP TARGETING AGENTS | Erasmus University Rotterdam Medical Center (NL) | 2024-03-27 | — | — | EP | claimed |
| WO-2023229458-A1 | RADIOISOTOPE LABELED SSTR2-AGONISTS WITH LINKERS | ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM (NL) | 2023-11-30 | — | — | WO | claimed |
| EP-4282439-A1 | RADIOISOTOPE LABELED SSTR2-AGONISTS WITH LINKERS | Erasmus University Rotterdam Medical Center (NL) | 2023-11-29 | — | — | EP | claimed |
| US-20180110658-A1 | Thin Patch | LIN HSUEH YA (TW) | 2018-04-26 | — | — | US | claimed |
| EP-2986117-A1 | BINARY INSECTICIDAL OR PESTICIDAL MIXTURE | Bayer CropScience Aktiengesellschaft (DE) | 2016-02-24 | — | — | EP | claimed |
| WO-2016001125-A1 | ACTIVE COMPOUND COMBINATIONS AND METHODS TO PROTECT THE PROPAGATION MATERIAL OF PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-07 | — | — | WO | claimed |
| US-20060018933-A1 | Novel drug delivery system | TORRENT PHARMACEUTICALS LIMITED (IN) | 2006-01-26 | — | — | US | claimed |
| US-20060018934-A1 | Novel drug delivery system | TORRENT PHARMACEUTICALS LIMITED (IN) | 2006-01-26 | — | — | US | claimed |
| EP-1581269-A1 | HAEMOSTATIC WOUND DRESSING | Langer, Hans-Georg (DE) | 2005-10-05 | — | — | EP | claimed |
| WO-2004054632-A1 | HAEMOSTATIC WOUND DRESSING | LANGER, HANS-GEORG (DE) | 2004-07-01 | — | — | WO | claimed |
| EP-0728730-B1 | Process for preparing monochloroacetic acid | SALZGITTER ANLAGENBAU GMBH (DE) | 2001-03-07 | — | — | EP | claimed |
| WO-1998000161-A1 | FIBRIN-BASED SYSTEMS FOR THE CONTROLLED RELEASE OF MEDICINALS | BUFORD BIOMEDICAL, INC. (US) | 1998-01-08 | — | — | WO | claimed |
| EP-0329105-B1 | MOLECULAR WEIGHT CONTROLLER FOR POLYMERIZATION OF LACTAMS TO POLYAMIDES | BASF Corporation (US) | 1993-07-07 | — | — | EP | claimed |
| US-5006635-A | Monofunctional amine, monofunctional acid, salt of aminoacid, polyamides | BASF CORPORATION (US) | 1991-04-09 | — | — | US | claimed |
| EP-0329105-A2 | Molecular weight controller for polymerization of lactams to polyamides | BASF Corporation (US) | 1989-08-23 | — | — | EP | claimed |
| US-4844834-A | Molecular weight controller for polymerization of lactams to polyamides | BASF CORPORATION (US) | 1989-07-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346589-A1 | RADIOISOTOPE LABELED SSTR2-AGONISTS WITH LINKERS | SSTR2, SSTR5, SSTR1 | PLG 2667/4885PLAT 3407/4885LMNA 1849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.