Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tranexamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG known ✓ | P00747 | 1/20 | 1.00 |
| ▸ | PLAT | P00750 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | ANPEP | P15144 | 1/20 | 0.52 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tranexamic Acid SCHEMBL423790 | 1.00 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL186034 | 1.00 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL349408 | 1.00 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL322487 | 1.00 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL19031783 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL3793503 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL11189660 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL10723480 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL7326280 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL29236634 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 33203 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144720-A1 | COSMETIC COMPOSITIONS CONTAINING PIGMENT PARTICLES IN A HYDROPHOBIC PHASE | ELC MANAGEMENT LLC (US) | 2026-05-28 | — | — | US | claimed |
| CN-122075319-A | Composition, and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-12636198-B2 | Bandage for providing protection and antimicrobial properties to a surgical site with one or more percutaneous pins or wires | ORTHOBARRIER TECHNOLOGIES LLC (US) | 2026-05-26 | — | — | US | claimed |
| US-12636249-B2 | Concentrated injectable tranexamic acid compositions and methods of use thereof | GALEN LIMITED (GB) | 2026-05-26 | — | — | US | claimed |
| CN-122081228-A | Method for constructing multiple myeloma individuation organoids based on rigidity gradient regulation and control and application | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075357-A | Composition with whitening and anti-wrinkle functions and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| EP-4744663-A2 | SKIN COMPOSITION | Eaderm Co., Ltd. (JP) | 2026-05-20 | — | — | EP | claimed |
| CN-122056795-A | A cosmetic composition with skin whitening and antiaging effects | 丝薇茜(上海)生物技术有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122036847-A | Acetyl tetrapeptide-2 and application thereof in freckle-removing and whitening cosmetics/daily necessities | 佛山中科仟合新材料有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122038573-A | DNA fiber bar code probe for detecting multiple miRNAs and application thereof | 山西医科大学第一医院 | 2026-05-15 | — | — | CN | claimed |
| US-4309410-A | TRANEXAMIC ACID AND TETRAPOTASSIUM PEROXYDIPHOSPHATE | COLGATE-PALMOLIVE COMPANY (US) | 1982-01-05 | — | — | US | claimed |
| US-4272512-A | TRANEXAMIC ACID AND FOLIC ACID | COLGATE-PALMOLIVE COMPANY (US) | 1981-06-09 | — | — | US | claimed |
| US-4272513-A | TRANEXAMIC ACID, FLUORINE-CONTAINING ANTICARIES AGENT, AND FLAVORING | COLGATE-PALMOLIVE COMPANY (US) | 1981-06-09 | — | — | US | claimed |
| US-4258030-A | ENZYME INHIBITOR AS STABILIZER | ZERIA-SHINYAKU KOGYO KABUSHIKI KAISHA (JP) | 1981-03-24 | — | — | US | claimed |
| US-4171377-A | ANTISWELLING AGENTS | Burton, Parsons & Co., Inc. (US) | 1979-10-16 | — | — | US | claimed |
| US-4071553-A | Method for the production of trans-4-aminomethyl cyclohexane-1-carboxylic acid | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1978-01-31 | — | — | US | claimed |
| US-4048222-A | P-AMINOMETHYLBENZOIC ACID, RUTHENIUM CATALYST | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1977-09-13 | — | — | US | claimed |
| US-3959253-A | β-D-glucosyluronic acid derivatives | MERCK & CO., INC. (US) | 1976-05-25 | — | — | US | claimed |
| US-3956503-A | 4-AMINOMETHYL-CYCLOHEXANECARBOXYLIC ACID | DAIICHI SEIYAKU CO., LTD. (JA) | 1976-05-11 | — | — | US | claimed |
| US-3950405-A | ANTIPLASMIN AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1976-04-13 | — | — | US | claimed |