SCHEMBL29237012

SCHEMBL29237012

Clc1cc(Cl)c2cc3cnccc3cc2n1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.45
CLK1 P49759 2/20 0.43
CSNK1D P48730 1/20 0.42
CSNK1E P49674 1/20 0.42
DYRK1A Q13627 1/20 0.42
HASPIN Q8TF76 11/20 0.41
CCNT1 O60563 4/20 0.41
CDK9 P50750 4/20 0.41
PIM1 P11309 3/20 0.41
IMPDH2 P12268 1/20 0.35
PRKCZ Q05513 1/20 0.34
KDM4E B2RXH2 1/20 0.34
KDM4A O75164 1/20 0.34
KDM5C P41229 1/20 0.34
KDM4D Q6B0I6 1/20 0.34
KDM4C Q9H3R0 1/20 0.34
PRKCI P41743 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29237022 1.00 MAPT (0.45) MAPTCLK1CSNK1DCSNK1EDYRK1A
SCHEMBL246231 0.80 LATS1 (0.43) IMPDH2KDM4EKDM4AKDM5CKDM4D
SCHEMBL4789438 0.78 HIPK2 (0.39) IMPDH2KDM4EKDM4AKDM5CKDM4D
SCHEMBL30969484 0.75 MAPT (0.40) MAPT
SCHEMBL29237018 0.75 MAPT (0.40) MAPT
SCHEMBL1018440 0.75 CLK1 (0.46) MAPTCLK1CSNK1DCSNK1EDYRK1A
Hydrochloric Acid SCHEMBL10671831 0.73 CLK1 (0.44) MAPTCLK1CSNK1DCSNK1EDYRK1A
SCHEMBL26998825 0.71 ACHE (0.40) MAPTDYRK1APIM1KDM4E
SCHEMBL445516 0.70 CLK1 (0.57) MAPTCLK1CSNK1DCSNK1EDYRK1A
SCHEMBL4036768 0.70 CLK1 (0.57) MAPTCLK1CSNK1DCSNK1EDYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117942786-A Preparation method of nanofiltration membrane and nanofiltration membrane prepared by same 沃顿科技股份有限公司 2024-04-30 CN disclosed