SCHEMBL30969484

SCHEMBL30969484

Clc1cc2cc3c(Cl)cc(Cl)nc3cc2cn1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.40
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29237018 1.00 MAPT (0.40) MAPTALDH1A1LMNA
SCHEMBL23301288 0.80 ALDH1A1 (0.36) MAPTALDH1A1LMNA
SCHEMBL29237012 0.75 MAPT (0.45) MAPT
SCHEMBL29237022 0.75 MAPT (0.45) MAPT
SCHEMBL26998825 0.73 ACHE (0.40) MAPTALDH1A1LMNA
SCHEMBL20951048 0.72 ALDH1A1 (0.36) ALDH1A1
SCHEMBL29972730 0.67 ALDH1A1 (0.48) ALDH1A1
SCHEMBL23576483 0.67 ALDH1A1 (0.48) ALDH1A1
SCHEMBL30656089 0.67 NT5E (0.36) MAPTLMNA
SCHEMBL16636878 0.67 NT5E (0.36) MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117942786-A Preparation method of nanofiltration membrane and nanofiltration membrane prepared by same 沃顿科技股份有限公司 2024-04-30 CN disclosed