Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967827 | 1.00 | ALDH1A1 (0.43) | ALDH1A1AKR1C1HCAR3HCAR2LMNA | |
| SCHEMBL4501046 | 0.91 | ALDH1A1 (0.48) | ALDH1A1AKR1C1HCAR3HCAR2LMNA | |
| SCHEMBL26105914 | 0.88 | HCAR3 (0.43) | ALDH1A1AKR1C1HCAR3HCAR2NPSR1 | |
| SCHEMBL30520969 | 0.88 | HCAR3 (0.43) | ALDH1A1AKR1C1HCAR3HCAR2NPSR1 | |
| SCHEMBL19331280 | 0.87 | ALOX5 (0.43) | ALDH1A1HCAR3HCAR2LMNANPSR1 | |
| SCHEMBL23886618 | 0.82 | AKR1C1 (0.58) | ALDH1A1AKR1C1LMNANPSR1TSHR | |
| SCHEMBL671822 | 0.82 | AKR1C1 (0.53) | ALDH1A1AKR1C1HCAR3HCAR2NPSR1 | |
| SCHEMBL12638722 | 0.81 | ALOX5 (0.44) | ALDH1A1HCAR3HCAR2LMNANPSR1 | |
| SCHEMBL332753 | 0.81 | ALOX5 (0.50) | ALDH1A1HCAR3HCAR2LMNANPSR1 | |
| SCHEMBL1492825 | 0.80 | AKR1C1 (0.59) | ALDH1A1AKR1C1HCAR3HCAR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |