Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30216992 | 1.00 | MTNR1A (0.38) | MTNR1AMTNR1BDGAT2AURKAAURKB | |
| SCHEMBL30967803 | 0.92 | DGAT2 (0.34) | MTNR1AMTNR1BDGAT2ROCK2CDK8 | |
| SCHEMBL30217176 | 0.92 | DGAT2 (0.34) | MTNR1AMTNR1BDGAT2ROCK2CDK8 | |
| SCHEMBL29237406 | 0.91 | DGAT2 (0.34) | MTNR1AMTNR1BDGAT2ROCK2CDK8 | |
| SCHEMBL30217287 | 0.91 | DGAT2 (0.34) | MTNR1AMTNR1BDGAT2ROCK2CDK8 | |
| SCHEMBL29336791 | 0.88 | DGAT2 (0.40) | MTNR1AMTNR1BDGAT2AURKAAURKB | |
| SCHEMBL30967771 | 0.87 | DGAT2 (0.33) | DGAT2ROCK2CDK8DNMT3BROCK1 | |
| SCHEMBL29237475 | 0.87 | DGAT2 (0.33) | DGAT2ROCK2CDK8DNMT3BROCK1 | |
| SCHEMBL30217168 | 0.87 | DGAT2 (0.33) | DGAT2ROCK2CDK8DNMT3BROCK1 | |
| SCHEMBL30217164 | 0.85 | DGAT2 (0.32) | DGAT2CDK8DNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |