Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13539340 | 0.76 | ALDH1A1 (0.64) | RXFP1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1616338 | 0.74 | SLC40A1 (0.48) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10044530 | 0.69 | RXFP1 (0.73) | RXFP1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5291639 | 0.68 | MEN1 (0.69) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL538070 | 0.68 | KMT2A (0.55) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3764297 | 0.67 | PIK3CD (0.76) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL20644791 | 0.67 | RXFP1 (0.68) | RXFP1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2055437 | 0.66 | RECQL (0.63) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL6383953 | 0.65 | HTT (0.49) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7569823 | 0.64 | PTPN1 (0.67) | MEN1KMT2AGLO1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099763-B1 | 2-AMINOQUINOLINES AS 5-HT(5A) RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2010-08-11 | — | — | EP | disclosed |