Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | ITGB2 | P05107 | 7/20 | 0.48 |
| ▸ | ITGAL | P20701 | 7/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30928278 | 1.00 | LRRK2 (0.50) | LRRK2FAAHITGB2ITGALICAM1 | |
| SCHEMBL902015 | 0.81 | ITGB2 (0.46) | ITGB2ITGALICAM1SMOCKS1B | |
| SCHEMBL15450884 | 0.74 | KDM4E (0.51) | SMOCKS1BSKP1SKP2ALDH1A1 | |
| SCHEMBL1704697 | 0.74 | KARS1 (0.71) | — | |
| SCHEMBL21193400 | 0.73 | NPC1 (0.50) | ITGB2ITGALICAM1SMOCKS1B | |
| SCHEMBL30803918 | 0.73 | NPC1 (0.50) | ITGB2ITGALICAM1SMOCKS1B | |
| SCHEMBL21193001 | 0.71 | FYN (0.61) | — | |
| SCHEMBL30803947 | 0.71 | FYN (0.61) | — | |
| SCHEMBL3442148 | 0.71 | FAAH (0.71) | FAAHSLC6A7ALDH1A1KDM4E | |
| SCHEMBL9932291 | 0.71 | MEN1 (0.48) | ITGB2ITGALICAM1SMOCKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005640-A | GCN2 inhibitors and uses thereof | 默克专利股份有限公司 | 2024-05-10 | — | — | CN | disclosed |