Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 11/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477428 | 0.96 | TBXAS1 (0.67) | TBXAS1ALDH1A1ABL1RIN1CYP19A1 | |
| SCHEMBL11474932 | 0.91 | TBXAS1 (0.67) | TBXAS1ALDH1A1ABL1RIN1CYP19A1 | |
| SCHEMBL10851510 | 0.86 | TBXAS1 (0.67) | TBXAS1ALDH1A1ABL1RIN1CYP19A1 | |
| SCHEMBL11475103 | 0.85 | CYP11B1 (0.54) | TBXAS1ALDH1A1ABL1RIN1CYP19A1 | |
| SCHEMBL29239321 | 0.83 | TBXAS1 (0.70) | TBXAS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11487884 | 0.80 | CYP11B1 (0.56) | TBXAS1ALDH1A1ABL1RIN1CYP19A1 | |
| SCHEMBL10657236 | 0.79 | TBXAS1 (0.74) | TBXAS1CYP19A1CYP11B1CYP11B2PLA2G4A | |
| SCHEMBL10851021 | 0.79 | CYP19A1 (0.54) | TBXAS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11484688 | 0.79 | TBXAS1 (0.68) | TBXAS1ALDH1A1CYP19A1 | |
| SCHEMBL14499226 | 0.79 | TBXAS1 (0.60) | TBXAS1ALDH1A1ABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005563-A | N-benzyl imidazole derivative and preparation method and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |