SCHEMBL29239387

SCHEMBL29239387

CN(C)Cc1nc(OC(N)=O)ccc1C1CCC(=O)C1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 1/20 0.32
PDE10A Q9Y233 1/20 0.31
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29239397 0.85 CNR2 (0.33)
SCHEMBL28876734 0.82 CNR2 (0.36)
SCHEMBL31330381 0.80 CNR2 (0.38)
SCHEMBL24992618 0.74 SCN9A (0.35)
SCHEMBL30172986 0.74 SCN9A (0.35)
SCHEMBL30172998 0.74 SCN9A (0.35)
SCHEMBL29150549 0.72 PARP1 (0.31)
SCHEMBL29239391 0.70
SCHEMBL29239409 0.68 GRM2 (0.37)
SCHEMBL28876524 0.68 CNR2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117915912-A HPK1 antagonists and uses thereof 林伯士萨顿公司 2024-04-19 CN disclosed