Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30173043 | 1.00 | KMT2A (0.41) | KMT2AABL1MEN1JAK1ADORA3 | |
| SCHEMBL29239384 | 1.00 | KMT2A (0.41) | KMT2AABL1MEN1JAK1ADORA3 | |
| SCHEMBL29239385 | 1.00 | KMT2A (0.41) | KMT2AABL1MEN1JAK1ADORA3 | |
| SCHEMBL30865558 | 0.78 | HSD11B1 (0.38) | — | |
| SCHEMBL24992530 | 0.77 | ADORA2B (0.46) | KMT2AABL1MEN1ADORA3HPGD | |
| SCHEMBL29239398 | 0.77 | ADORA2B (0.46) | KMT2AABL1MEN1ADORA3HPGD | |
| SCHEMBL30173072 | 0.77 | ADORA2B (0.46) | KMT2AABL1MEN1ADORA3HPGD | |
| SCHEMBL29086163 | 0.70 | CHRM2 (0.37) | KMT2AMEN1HTTMAPT | |
| SCHEMBL29086164 | 0.70 | CHRM2 (0.37) | KMT2AMEN1HTTMAPT | |
| SCHEMBL29086162 | 0.70 | CHRM2 (0.37) | KMT2AMEN1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117915912-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2024-04-19 | — | — | CN | disclosed |