Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | HTR1F | P30939 | 4/20 | 0.42 |
| ▸ | HTR1D | P28221 | 3/20 | 0.42 |
| ▸ | HTR1B | P28222 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30173072 | 1.00 | ADORA2B (0.46) | ADORA2BADORA2AADORA1ADORA3HPGD | |
| SCHEMBL24992530 | 1.00 | ADORA2B (0.46) | ADORA2BADORA2AADORA1ADORA3HPGD | |
| SCHEMBL30173075 | 0.78 | ADORA2B (0.40) | ADORA2BADORA2AADORA1ADORA3HPGD | |
| SCHEMBL29239372 | 0.78 | ADORA2B (0.40) | ADORA2BADORA2AADORA1ADORA3HPGD | |
| SCHEMBL29239386 | 0.78 | HTR1A (0.41) | HPGDHTR1AHTR1FHTR1DHTR1B | |
| SCHEMBL24992531 | 0.78 | HTR1A (0.41) | HPGDHTR1AHTR1FHTR1DHTR1B | |
| SCHEMBL30173054 | 0.78 | HTR1A (0.41) | HPGDHTR1AHTR1FHTR1DHTR1B | |
| SCHEMBL29239375 | 0.78 | ADORA2B (0.40) | ADORA2BADORA2AADORA1ADORA3HPGD | |
| SCHEMBL29239385 | 0.77 | KMT2A (0.41) | ADORA3HPGDABL1NPC1RAB9A | |
| SCHEMBL29239384 | 0.77 | KMT2A (0.41) | ADORA3HPGDABL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117915912-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2024-04-19 | — | — | CN | disclosed |