Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952929 | 0.84 | ACHE (0.44) | MAPTTDP1 | |
| SCHEMBL3757645 | 0.79 | KDM4E (0.50) | MAPTTDP1GAAALDH1A1HTT | |
| SCHEMBL29953103 | 0.79 | KDM4E (0.50) | MAPTTDP1GAAALDH1A1HTT | |
| SCHEMBL1459513 | 0.78 | ALOX15 (0.49) | MAPTTDP1GAAALDH1A1HTT | |
| SCHEMBL23682923 | 0.78 | MAPT (0.49) | MAPTTDP1GAAALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL29958669 | 0.78 | KDM4E (0.49) | MAPTTDP1GAAALDH1A1HTT | |
| SCHEMBL3278794 | 0.78 | MAPT (0.66) | MAPTTDP1GAAALDH1A1HTT | |
| SCHEMBL10001173 | 0.76 | KDM4E (0.50) | MAPTTDP1GAAALDH1A1MAPK1 | |
| SCHEMBL629923 | 0.75 | KDM4E (0.64) | MAPTTDP1GAAALDH1A1HTT | |
| SCHEMBL29957691 | 0.75 | KDM4E (0.64) | MAPTTDP1GAAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250042914-A1 | PIKFYVE KINASE INHIBITOR | HANMI PHARM. CO., LTD. (KR) | 2025-02-06 | — | — | US | disclosed |
| EP-4410795-A1 | PIKFYVE KINASE INHIBITOR | Hanmi Pharm. Co., Ltd. (KR) | 2024-08-07 | — | — | EP | disclosed |
| CN-118019744-A | PIKfyve kinase inhibitors | 韩美药品株式会社 | 2024-05-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250042914-A1 | PIKFYVE KINASE INHIBITOR | PIKFYVE, PIP4K2B, PIP4K2C | MAPT 2647/4885TDP1 424/4885GAA 1842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.