Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.50 |
| ▸ | GAA | P10253 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PLEC | Q15149 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953103 | 1.00 | KDM4E (0.50) | KDM4EGAAMAPTALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL29958669 | 0.98 | KDM4E (0.49) | KDM4EGAAMAPTALDH1A1THRB | |
| SCHEMBL28154507 | 0.82 | MAPK1 (0.54) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL629923 | 0.79 | KDM4E (0.64) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL29957691 | 0.79 | KDM4E (0.64) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL29239643 | 0.79 | MAPT (0.39) | KDM4EGAAMAPTALDH1A1THRB | |
| SCHEMBL29952929 | 0.78 | ACHE (0.44) | MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL29952442 | 0.78 | KDM4E (0.62) | KDM4EGAAMAPTALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL629029 | 0.78 | KDM4E (0.62) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL29950782 | 0.78 | TSHR (0.50) | KDM4EGAAMAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396225-B | Metal organic frame material for zinc-air battery, ligand and application thereof | 吉林省卓材新研科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116253694-B | Ligand, metal organic framework material, application of ligand and metal organic framework material and perovskite solar cell | 吉林省卓材新研科技有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116396225-A | Metal organic frame material for zinc-air battery, ligand and application thereof | 吉林省卓材新研科技有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-116253694-A | Ligand, metal organic framework material, application of ligand and metal organic framework material and perovskite solar cell | 吉林省卓材新研科技有限公司 | 2023-06-13 | — | — | CN | disclosed |
| US-11021435-B2 | Serotonin receptor-targeting compounds and methods | NORTHEASTERN UNIVERSITY (US) | 2021-06-01 | — | — | US | disclosed |
| US-10548856-B2 | Compounds and methods for modulating serotonin receptors in the periphery | NORTHEASTERN UNIVERSITY (US) | 2020-02-04 | — | — | US | disclosed |
| US-20180125798-A1 | Compounds and Methods for Modulating Serotonin Receptors in the Periphery | NORTHEASTERN UNIVERSITY | 2018-05-10 | — | — | US | disclosed |
| US-20170081273-A1 | Serotonin Receptor-Targeting Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-03-23 | — | — | US | disclosed |
| EP-2029570-B1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2014-10-15 | — | — | EP | disclosed |
| US-8324204-B2 | Fused thiophene derivatives as kinase inhibitors | UCB PHARMA SA (BE) | 2012-12-04 | — | — | US | disclosed |
| US-20100305066-A1 | Fused Thiophene Derivatives as Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2010-12-02 | — | — | US | disclosed |
| EP-2029570-A1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma S.A. (BE) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007141504-A1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2007-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180125798-A1 | Compounds and Methods for Modulating Serotonin Receptors in the Periphery | HTR5A, HTR3A, HTR1A | KDM4E 4217/4885GAA 3819/4885MAPT 1771/4885 |
| US-20100305066-A1 | Fused Thiophene Derivatives as Kinase Inhibitors | PIKFYVE, PI4KA, PIK3CA | KDM4E 1014/4885GAA 1593/4885MAPT 790/4885 |
| US-10548856-B2 | Compounds and methods for modulating serotonin receptors in the periphery | HTR5A, HTR3A, HTR1A | KDM4E 4217/4885GAA 3819/4885MAPT 1771/4885 |
| US-11021435-B2 | Serotonin receptor-targeting compounds and methods | HTR1A, HTR2C, HTR7 | KDM4E 2965/4885GAA 4506/4885MAPT 1069/4885 |
| US-20170081273-A1 | Serotonin Receptor-Targeting Compounds and Methods | HTR1A, HTR2C, HTR7 | KDM4E 2965/4885GAA 4506/4885MAPT 1069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.