Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138297 | 0.74 | MEN1 (0.34) | MEN1KMT2AOPRM1OPRL1OPRK1 | |
| SCHEMBL9562288 | 0.69 | CHRNA7 (0.36) | MEN1MAPTCYP2C9CYP2C19KMT2A | |
| SCHEMBL296400 | 0.69 | MAOA (0.43) | OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL29239722 | 0.68 | ALDH1A1 (0.37) | — | |
| SCHEMBL19358804 | 0.68 | HCN1 (0.30) | OPRM1OPRL1OPRK1 | |
| SCHEMBL14039576 | 0.68 | — | — | |
| SCHEMBL29239659 | 0.67 | HRH4 (0.32) | MEN1MAPTCYP2C9CYP2C19KMT2A | |
| SCHEMBL25417165 | 0.67 | — | — | |
| SCHEMBL17431790 | 0.67 | MEN1 (0.40) | MEN1MAPTKMT2AOPRM1OPRL1 | |
| SCHEMBL351946 | 0.65 | EPHX1 (0.39) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591319-B | Tetrahydropyridopyrimidine derivative and application thereof | 江苏先声药业有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-114591319-A | Tetrahydropyridopyrimidine derivative and application thereof | 江苏先声药业有限公司 | 2022-06-07 | — | — | CN | disclosed |