SCHEMBL29240297

SCHEMBL29240297

CC(C)(C)c1cc(-c2ccccc2)c(N)c(C(C)(C)C)c1C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 2/20 0.36
SMARCA2 P51531 1/20 0.34
SMARCA4 P51532 1/20 0.34
PBRM1 Q86U86 1/20 0.34
BACE1 P56817 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
PLAU P00749 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
MAPT P10636 1/20 0.33
IKBKB O14920 1/20 0.32
CHUK O15111 1/20 0.32
IKBKE Q14164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28480301 0.89 PDE4A (0.37) ALDH1A1HSD17B10SMARCA2SMARCA4PBRM1
SCHEMBL9523811 0.85 CA2 (0.41) ALDH1A1BACE1MEN1KMT2ATSHR
SCHEMBL4461656 0.83 BACE1 (0.37) ALDH1A1HSD17B10BACE1PLAUADORA3
SCHEMBL5240821 0.80 BACE1 (0.34) ALDH1A1BACE1ADORA3ADORA2AADORA1
SCHEMBL1071427 0.80 BACE1 (0.34) ALDH1A1BACE1ADORA3ADORA2AADORA1
SCHEMBL28882059 0.80 ALDH1A1 (0.38) ALDH1A1HSD17B10SMARCA2SMARCA4PBRM1
SCHEMBL28622378 0.79 HSD17B10 (0.36) ALDH1A1HSD17B10SMARCA2SMARCA4PBRM1
SCHEMBL28055506 0.76 ALDH1A1 (0.38) ALDH1A1HSD17B10SMARCA2SMARCA4PBRM1
SCHEMBL24570933 0.75 PDE4A (0.37) ALDH1A1HSD17B10SMARCA2SMARCA4PBRM1
SCHEMBL4756144 0.75 HSP90AA1 (0.41) ALDH1A1HSD17B10SMARCA2SMARCA4PBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118265429-A Organic light-emitting element 吉林省元合电子材料有限公司 2024-06-28 CN disclosed