SCHEMBL28622378

SCHEMBL28622378

CC(C)(C)c1cc(N)cc(-c2ccccc2)c1C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAOA P21397 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
CYP3A4 P08684 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
SMARCA2 P51531 1/20 0.34
SMARCA4 P51532 1/20 0.34
PBRM1 Q86U86 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
BACE1 P56817 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
GAA P10253 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4461656 0.79 BACE1 (0.37) HSD17B10ALDH1A1TDP1MEN1KMT2A
SCHEMBL29240297 0.79 ALDH1A1 (0.36) HSD17B10ALDH1A1MAOATDP1SMARCA2
SCHEMBL29022931 0.79 ALDH1A1 (0.44) HSD17B10ALDH1A1TDP1MEN1KMT2A
SCHEMBL27008526 0.79 METAP2 (0.38) ALDH1A1TDP1MEN1KMT2ABACE1
SCHEMBL28807708 0.78 TSHR (0.44) HSD17B10ALDH1A1MAOATDP1CYP3A4
SCHEMBL1071427 0.76 BACE1 (0.34) ALDH1A1TDP1MEN1KMT2ABACE1
SCHEMBL5240821 0.76 BACE1 (0.34) ALDH1A1TDP1MEN1KMT2ABACE1
SCHEMBL28985273 0.75 ALDH1A1 (0.36) ALDH1A1TDP1MEN1KMT2ABACE1
SCHEMBL28480301 0.75 PDE4A (0.37) HSD17B10ALDH1A1MAOATDP1SMARCA2
SCHEMBL1194487 0.73 CA2 (0.41) HSD17B10ALDH1A1TDP1BACE1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113906580-A Organic light emitting element 株式会社LG化学 2022-01-07 CN disclosed
CN-113348172-A Compound and organic light emitting device including the same 株式会社LG化学 2021-09-03 CN disclosed