Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16139570 | 0.82 | CHRNB2 (0.41) | CHRNB2CHRNA4 | |
| SCHEMBL32671187 | 0.80 | CHRNB2 (0.33) | CHRNB2CHRNA4PPARG | |
| SCHEMBL335593 | 0.74 | CHRNB2 (0.38) | CHRNB2CHRNA4 | |
| SCHEMBL24424401 | 0.73 | PRMT5 (0.33) | PPARG | |
| SCHEMBL5021673 | 0.71 | CHRNB2 (0.36) | CHRNB2CHRNA4 | |
| SCHEMBL29404818 | 0.71 | GRM4 (0.34) | CHRNB2CHRNA4 | |
| SCHEMBL27214435 | 0.70 | NOS3 (0.47) | PPARG | |
| SCHEMBL31247421 | 0.70 | FPR2 (0.33) | — | |
| SCHEMBL16139573 | 0.69 | CHRNB2 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL12609562 | 0.67 | CHRNB2 (0.45) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |