Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COXFA4 | O00483 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29244241 | 0.89 | COXFA4 (0.48) | COXFA4ALDH1A1GAAHPGDMAPT | |
| SCHEMBL30874666 | 0.89 | COXFA4 (0.48) | COXFA4ALDH1A1GAAHPGDMAPT | |
| SCHEMBL30874638 | 0.89 | GAA (0.49) | COXFA4ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL29244234 | 0.89 | GAA (0.49) | COXFA4ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL29244240 | 0.88 | COXFA4 (0.47) | COXFA4ALDH1A1GAAHPGDMAPT | |
| SCHEMBL30874665 | 0.88 | ALDH1A1 (0.49) | COXFA4ALDH1A1GAAHPGDMAPT | |
| SCHEMBL30874687 | 0.88 | COXFA4 (0.47) | COXFA4ALDH1A1GAAHPGDMAPT | |
| SCHEMBL29244242 | 0.88 | ALDH1A1 (0.49) | COXFA4ALDH1A1GAAHPGDMAPT | |
| SCHEMBL30874717 | 0.88 | NPC1 (0.46) | COXFA4ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL29244244 | 0.88 | NPC1 (0.46) | COXFA4ALDH1A1HPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946055-A | Chromene aryl hydrazide derivative and preparation method and application thereof | 贵州医科大学 | 2024-04-30 | — | — | CN | disclosed |