Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COXFA4 | O00483 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29244241 | 1.00 | COXFA4 (0.48) | COXFA4PTGS2NPC1RAB9ARARA | |
| SCHEMBL30874687 | 0.89 | COXFA4 (0.47) | COXFA4NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL29244240 | 0.89 | COXFA4 (0.47) | COXFA4NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL30874665 | 0.89 | ALDH1A1 (0.49) | COXFA4PTGS2NPC1RAB9ARARA | |
| SCHEMBL29244242 | 0.89 | ALDH1A1 (0.49) | COXFA4PTGS2NPC1RAB9ARARA | |
| SCHEMBL29244237 | 0.89 | COXFA4 (0.49) | COXFA4PTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29244235 | 0.87 | COXFA4 (0.53) | COXFA4PTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30874650 | 0.87 | COXFA4 (0.53) | COXFA4PTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30874638 | 0.87 | GAA (0.49) | COXFA4NPC1RAB9ASMN1; SMN2HIF1A | |
| SCHEMBL29244234 | 0.87 | GAA (0.49) | COXFA4NPC1RAB9ASMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946055-A | Chromene aryl hydrazide derivative and preparation method and application thereof | 贵州医科大学 | 2024-04-30 | — | — | CN | disclosed |