Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 4/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | ESRRA | P11474 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10309762 | 0.88 | CFTR (0.49) | CFTRNOTUMKDM4EALDH1A1MAPT | |
| SCHEMBL2769865 | 0.86 | CA12 (0.48) | CFTRNOTUMKDM4EALDH1A1MAPT | |
| SCHEMBL29338521 | 0.85 | CFTR (0.50) | CFTRNOTUMKDM4EALDH1A1MAPT | |
| SCHEMBL2409208 | 0.83 | SMN1; SMN2 (0.44) | CFTRNOTUMKDM4EALDH1A1MAPT | |
| SCHEMBL3898889 | 0.82 | CFTR (0.44) | CFTRNOTUMKDM4EALDH1A1MAPT | |
| SCHEMBL3661976 | 0.82 | CES2 (0.44) | KDM4EALDH1A1HPGDHSD17B10CES2 | |
| SCHEMBL2495129 | 0.81 | CFTR (0.43) | CFTRNOTUMKDM4EALDH1A1MAPT | |
| SCHEMBL20178593 | 0.81 | PPARA (0.46) | CFTRNOTUMKDM4EALDH1A1HPGD | |
| SCHEMBL6120235 | 0.81 | NOTUM (0.46) | CFTRNOTUMKDM4EALDH1A1MAPT | |
| SCHEMBL1022658 | 0.80 | ALDH1A1 (0.53) | KDM4EALDH1A1MAPTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151501-A1 | NOVEL IMIDAZOPYRIMIDINE COMPOUND AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024151501-A1 | NOVEL IMIDAZOPYRIMIDINE COMPOUND AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2024-07-18 | — | — | WO | disclosed |
| CN-118239926-A | TLR7 and 8 inhibitors, preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |