SCHEMBL2769865

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10309762	0.89	CFTR (0.49)	CA12CA2CA7CA9CA14
	SCHEMBL29244656	0.86	CFTR (0.47)	CA12CA2CA7CA9CA14
	SCHEMBL29338521	0.86	CFTR (0.50)	CA12CA2CA7CA9CA14
	SCHEMBL3898889	0.84	CFTR (0.44)	CFTRNOTUMKDM4EALDH1A1HPGD
	SCHEMBL2495129	0.82	CFTR (0.43)	CA12CA2CA7CA9CA14
	SCHEMBL20178593	0.82	PPARA (0.46)	CFTRNOTUMKDM4EALDH1A1HPGD
	SCHEMBL3670006	0.82	CES2 (0.46)	CA12CA2CA7CA9CA14
	SCHEMBL6477497	0.80	CA12 (0.55)	CA12CA2CA7CA9CA14
	SCHEMBL2504798	0.80	MLYCD (0.40)	GAACES2ESRRGKIF11AR
	SCHEMBL29338505	0.79	CFTR (0.41)	CA12CA2CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.