Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.31 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29246322 | 0.91 | DGAT1 (0.36) | DGAT1KMT2ANPC1MAPT | |
| SCHEMBL31019222 | 0.91 | DGAT1 (0.36) | DGAT1KMT2ANPC1MAPT | |
| SCHEMBL30421232 | 0.76 | DGAT1 (0.34) | DGAT1PTPN1NPC1 | |
| SCHEMBL30421153 | 0.74 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL30421657 | 0.71 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL20455667 | 0.71 | DGAT1 (0.38) | DGAT1PTPN1NPC1MAPT | |
| SCHEMBL29659291 | 0.71 | DGAT1 (0.38) | DGAT1PTPN1NPC1MAPT | |
| SCHEMBL27741684 | 0.70 | DGAT1 (0.38) | DGAT1KLKB1PTPN1MEN1KMT2A | |
| SCHEMBL31748342 | 0.70 | KEAP1 (0.41) | DGAT1KLKB1PTPN1NPC1 | |
| SCHEMBL21818656 | 0.69 | DGAT1 (0.35) | DGAT1KLKB1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118284608-A | Compounds as BCL-2 inhibitors | 重庆复创医药研究有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118215661-A | Compounds as BCL-2 inhibitors | 重庆复创医药研究有限公司 | 2024-06-18 | — | — | CN | disclosed |