SCHEMBL29246789

SCHEMBL29246789

C=CC(C)CC(OC(CC(C)C=C)c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.35
TRPA1 O75762 4/20 0.35
LMNA P02545 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ADRA2A P08913 1/20 0.34
ADRA2C P18825 1/20 0.34
HIF1A Q16665 1/20 0.34
SLC6A4 P31645 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CYP2C19 P33261 1/20 0.33
CACNA1F O60840 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
ADRA2B P18089 1/20 0.33
CHRM3 P20309 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
OPRK1 P41145 1/20 0.33
CACNA1D Q01668 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31274030 0.80 PABPC1 (0.47) TRPA1LMNAALDH1A1CYP2C19HPGD
SCHEMBL7450493 0.78 TAAR1 (0.41) TAAR1TRPA1LMNAKDM4EADRA2A
SCHEMBL31274486 0.76 LMNA (0.50) TRPA1LMNAKDM4EADRA2AADRA2C
SCHEMBL8986601 0.75 LMNA (0.47) TAAR1TRPA1LMNAKDM4EADRA2A
SCHEMBL939842 0.72 CYP2C19 (0.50) TAAR1KDM4ESLC6A4ALDH1A1CYP2C19
SCHEMBL9251514 0.72 KDM4E (0.41) TAAR1TRPA1LMNAKDM4EADRA2A
SCHEMBL29106741 0.71 LMNA (0.44) TAAR1TRPA1LMNAKDM4EADRA2A
Methane SCHEMBL28626702 0.71 CYP2C19 (0.48) TAAR1KDM4ESLC6A4ALDH1A1CYP2C19
SCHEMBL12525111 0.71 TAAR1 (0.39) TAAR1TRPA1LMNAHIF1ASLC6A4
SCHEMBL7449480 0.70 POLB (0.44) TAAR1LMNAKDM4EADRA2AADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084725-A 1-Cyano 2-hydroxy compound and preparation method thereof 南京工业大学 2024-05-28 CN claimed
CN-118084725-A 1-Cyano 2-hydroxy compound and preparation method thereof 南京工业大学 2024-05-28 CN disclosed