SCHEMBL292473

SCHEMBL292473

O=C(O)C(=O)CC(=O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 2/20 0.53
MAPK1 P28482 1/20 0.47
SLC13A3 Q8WWT9 1/20 0.47
EGLN1 Q9GZT9 1/20 0.47
FEN1 P39748 9/20 0.46
ERCC5 P28715 8/20 0.46
PTPN1 P18031 2/20 0.46
LDHA P00338 1/20 0.43
SRR Q9GZT4 1/20 0.43
HAO1 Q9UJM8 3/20 0.42
CA4 P22748 2/20 0.40
KDM5B Q9UGL1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxaloacetate SCHEMBL898612 0.84 LDHA (0.57) OR51E2MAPK1SLC13A3EGLN1FEN1
Oxaloacetate SCHEMBL4298763 0.84 LDHA (0.57) OR51E2MAPK1SLC13A3EGLN1FEN1
Oxaloacetate SCHEMBL8464 0.84
SCHEMBL29988180 0.83 OR51E2 (0.40) OR51E2MAPK1SLC13A3EGLN1FEN1
Oxaloacetate SCHEMBL25210523 0.81
Oxaloacetate SCHEMBL9782818 0.81 LDHA (0.53) OR51E2MAPK1SLC13A3EGLN1FEN1
Oxaloacetate SCHEMBL6545256 0.81 LDHA (0.53) OR51E2MAPK1SLC13A3EGLN1FEN1
Oxaloacetate SCHEMBL20912993 0.81 LDHA (0.53) OR51E2MAPK1SLC13A3EGLN1FEN1
Oxaloacetate SCHEMBL8638879 0.81 LDHA (0.53) OR51E2MAPK1SLC13A3EGLN1FEN1
Oxaloacetate SCHEMBL6545252 0.81 LDHA (0.53) OR51E2MAPK1SLC13A3EGLN1FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12162977-B2 Blocked polyisocyanate crosslinking agent, its preparation method and a coating composition comprising the same BASF COATINGS GMBH (DE) 2024-12-10 US claimed
CN-114729100-B Blocked polyisocyanate crosslinking agent, process for producing the same and coating composition comprising the same 巴斯夫涂料有限公司 2024-04-16 CN claimed
US-20220389153-A1 A BLOCKED POLYISOCYANATE CROSSLINKING AGENT, ITS PREPARATION METHOD AND A COATING COMPOSITION COMPRISING THE SAME BASF COATINGS GMBH (DE) 2022-12-08 US claimed
EP-4058500-A1 A BLOCKED POLYISOCYANATE CROSSLINKING AGENT, ITS PREPARATION METHOD AND A COATING COMPOSITION COMPRISING THE SAME BASF Coatings GmbH (DE) 2022-09-21 EP claimed
CN-114729100-A Blocked polyisocyanate crosslinkers, process for their preparation and coating compositions comprising the crosslinkers 巴斯夫涂料有限公司 2022-07-08 CN claimed
WO-2021094237-A1 A BLOCKED POLYISOCYANATE CROSSLINKING AGENT, ITS PREPARATION METHOD AND A COATING COMPOSITION COMPRISING THE SAME BASF COATINGS GMBH (DE) 2021-05-20 WO claimed
CN-119219841-A Hydrogel material with similar skin mechanical properties and preparation method thereof 深圳百变天使科技有限公司 2024-12-31 CN disclosed
US-12162977-B2 Blocked polyisocyanate crosslinking agent, its preparation method and a coating composition comprising the same BASF COATINGS GMBH (DE) 2024-12-10 US disclosed
CN-114729100-B Blocked polyisocyanate crosslinking agent, process for producing the same and coating composition comprising the same 巴斯夫涂料有限公司 2024-04-16 CN disclosed
WO-2024041139-A1 METHOD FOR DETECTING PROTEIN HAVING CHANGES IN ENERGY STATE, OR AFFINITY OF LIGAND TO PROTEIN 中国科学院大连化学物理研究所 2024-02-29 WO disclosed
US-20230365831-A1 A COATING COMPOSITION, ITS PREPARATION AND USE THEREOF BASF COATINGS GMBH (DE) 2023-11-16 US disclosed
EP-4214261-A1 A COATING COMPOSITION, ITS PREPARATION AND USE THEREOF BASF Coatings GmbH (DE) 2023-07-26 EP disclosed
CN-116194504-A Coating composition, its preparation and use 巴斯夫涂料有限公司 2023-05-30 CN disclosed
EP-0706517-B1 PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY NISSAN CHEMICAL IND LTD (JP) 1998-10-21 EP disclosed
US-5728702-A BRONCHODILATOR AGENTS, ANTIALLERGENS OR ANTIPLATELET DRUGGS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-17 US disclosed
EP-0706517-A1 PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1996-04-17 EP disclosed
EP-0408255-B1 Thermoplastic resin composition SUMITOMO CHEMICAL CO (JP) 1995-05-17 EP disclosed
WO-1995001343-A1 PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1995-01-12 WO disclosed
US-5284681-A Bringing into contact with water, drying in air SUMITOMO CHEMICAL CO., LTD. (JP) 1994-02-08 US disclosed
US-5182151-A Polyphenylene ether, propylene graft polymer, rubber, molding material SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-01-26 US disclosed