Oxaloacetate

Oxaloacetate

SCHEMBL20912993

C.O=C(O)CC(=O)C(=O)O

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LDHA P00338 1/20 0.53
▸ SRR Q9GZT4 1/20 0.53
▸ OR51E2 Q9H255 3/20 0.47
▸ EGLN1 Q9GZT9 2/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ SLC13A3 Q8WWT9 1/20 0.47
▸ FEN1 P39748 6/20 0.40
▸ ERCC5 P28715 5/20 0.40
▸ PTPN1 P18031 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ HAO1 Q9UJM8 3/20 0.37
▸ ALOX15 P16050 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ LMNA P02545 1/20 0.35
▸ ALKBH5 Q6P6C2 1/20 0.35
▸ SUCNR1 Q9BXA5 1/20 0.35
▸ FFAR3 O14843 1/20 0.33
▸ GLRA1 P23415 1/20 0.33
▸ SLC6A9 P48067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxaloacetate SCHEMBL6310306 1.00 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL4298763 0.96 LDHA (0.57) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL8464 0.96 — —
Oxaloacetate SCHEMBL898612 0.96 LDHA (0.57) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL25210523 0.93 — —
Oxaloacetate SCHEMBL11328361 0.93 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL9782818 0.93 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL8638879 0.93 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL9994505 0.93 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL6545252 0.93 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190119193-A1 COMPOSITION FOR REGULATING PLANT GROWTH, METHOD FOR TREATING PLANTS THEREWITH, AND ACTIVE INGREDIENT THEREOF Ivan Aleksandrovich Starikov 2019-04-25 — — US disclosed
EP-3473098-A1 COMPOSITION FOR REGULATING PLANT GROWTH, METHOD FOR TREATING PLANTS THEREWITH, AND ACTIVE INGREDIENT THEREOF Gorbunov, Sergei Valeryevich (RU) 2019-04-24 — — EP disclosed
CN-105505892-B The production method of 2,4- dihydroxy butyric acid 安迪苏法国联合股份有限公司 2019-03-26 — — CN disclosed
CN-104254612-B A kind of production method of 2,4- dihydroxy butyric acid 安迪苏法国联合股份有限公司 2018-06-01 — — CN disclosed
CN-105505892-A Method for producing 2,4-dihydroxybutyric acid ADISSEO FRANCE SAS 2016-04-20 — — CN disclosed
CN-105497014-A Compositions and methods for improving mitochondrial functions AMAZENTIS SA 2016-04-20 — — CN disclosed
CN-103442594-B Compositions and methods for improving mitochondrial function and treating neurodegenerative diseases and cognitive disorders AMAZENTIS S.A. (CH) 2016-02-17 — — CN disclosed
CN-103270155-B Method for producing 2, 4-dihydroxybutyric acid ADISSEO FRANCE S.A.S. (FR) 2016-02-10 — — CN disclosed
CN-104254612-A A method of production of 2,4-dihydroxybutyric acid ADISSEO FRANCE SAS 2014-12-31 — — CN disclosed
CN-103270155-A Method for producing 2, 4-dihydroxybutyric acid ADISSEO FRANCE SAS 2013-08-28 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190119193-A1 COMPOSITION FOR REGULATING PLANT GROWTH, METHOD FOR TREATING PLANTS THEREWITH, AND ACTIVE INGREDIENT THEREOF OGDH, GOT1, OAT LDHA 476/4885SRR 727/4885OR51E2 2348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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