Oxaloacetate

Oxaloacetate

SCHEMBL4298763

O=C(O)CC(=O)C(=O)O.[NaH]

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.57
SRR Q9GZT4 1/20 0.57
OR51E2 Q9H255 3/20 0.50
EGLN1 Q9GZT9 2/20 0.50
MAPK1 P28482 1/20 0.50
SLC13A3 Q8WWT9 1/20 0.50
FEN1 P39748 4/20 0.42
ERCC5 P28715 3/20 0.42
PTPN1 P18031 1/20 0.42
TSHR P16473 3/20 0.41
KDM4E B2RXH2 1/20 0.41
HAO1 Q9UJM8 3/20 0.39
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LMNA P02545 1/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
SUCNR1 Q9BXA5 1/20 0.38
FFAR3 O14843 1/20 0.35
GLRA1 P23415 1/20 0.35
SLC6A9 P48067 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxaloacetate SCHEMBL898612 1.00 LDHA (0.57) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL8464 1.00
Oxaloacetate SCHEMBL6545252 0.96 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL20912993 0.96 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL9994505 0.96 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL25210523 0.96
Oxaloacetate SCHEMBL6545256 0.96 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL9782818 0.96 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL11328361 0.96 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL8638879 0.96 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107602809-A High-solid content water-based polyurethane dispersion liquid a kind of while based on aminocarboxylate and sulfamate 温州大学 2018-01-19 CN claimed
CN-107223125-B SGC stimulant 赛科理音医疗有限公司 2019-09-27 CN disclosed
CN-109568496-A The Chinese medicine composition treating the method for diabetes and using 陈浩 2019-04-05 CN disclosed
CN-109486872-A Stream plus the method for calcium agent in a kind of Citric Acid Fermentation 日照金禾博源生化有限公司 2019-03-19 CN disclosed
CN-108853275-A External Miao medicine liquid for repairing wound surface without leaving scar after healing and preparation method 庞栋升 2018-11-23 CN disclosed
CN-108431014-A Novel 5-azido-5-deoxy-2: 3-isopropylidene-D-arabinose compound, preparation method and application thereof in synthesizing ARA-N3, KDO-N3 and 4EKDO-N3 国家科研中心 2018-08-21 CN disclosed
CN-107296841-A The antidepression prescription of unobstructed qi and blood 合肥川迪医药技术有限公司 2017-10-27 CN disclosed
CN-107223125-A SGC stimulants 铁木医药有限公司 2017-09-29 CN disclosed
CN-104039977-B Method for specifically marking live bacteria 国家科学研究中心 2016-06-08 CN disclosed
CN-105063072-A Aldolases, nucleic acids encoding them and methods for making and using them VERENIUM CORP 2015-11-18 CN disclosed
CN-101437954-A Aldolases, nucleic acids encoding them and methods for making and using them CARGILL INC (US) 2009-05-20 CN disclosed
CN-101365787-A Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors CARGILL INC (US) 2009-02-11 CN disclosed
CN-100444864-C Chinese medicinal formulation for rehabilitating pancreatic islet function and decreasing blood sugar and preparation process thereof YIREN MIAO (CN) 2008-12-24 CN disclosed
CN-100387270-C A Chinese medicinal preparation for treating and preventing diabetes and its angiopathy SHANGHAI FANGXIN TECHNOLOGY IN (CN) 2008-05-14 CN disclosed
CN-101115505-A Methods and compositions for treating mammalian diseases and wounds caused by peroxynitrite overexpression NORTH CELL PHARMACEUTICAL INC (US) 2008-01-30 CN disclosed
CN-1317014-C Soaking bath Chinese medicine for treating diabetes HOU ZHENTAI (CN) 2007-05-23 CN disclosed
CN-1768807-A Chinese medicinal formulation for rehabilitating pancreatic islet function and decreasing blood sugar and preparation process thereof MIAO YIREN (CN) 2006-05-10 CN disclosed
CN-1759043-A Safety containers for biologically active substances and method for producing said container BAXTER HEALTHCARE SA (CH) 2006-04-12 CN disclosed
CN-1754546-A A Chinese medicinal preparation for treating and preventing diabetes and its angiopathy SHANGHAI FANGXIN TECHNOLOGY IN (CN) 2006-04-05 CN disclosed
CN-1709306-A Soaking bath Chinese medicine for treating diabetes HOU ZHENTAI (CN) 2005-12-21 CN disclosed