Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.37 |
| ▸ | PPARD | Q03181 | 12/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28770518 | 0.86 | PPARG (0.40) | PPARGPPARDFFAR1PPARATHRA | |
| SCHEMBL28577548 | 0.78 | MAOB (0.42) | DRD2MAOB | |
| SCHEMBL27668220 | 0.74 | CHEK1 (0.39) | MAOB | |
| SCHEMBL29248386 | 0.73 | LMNA (0.33) | PPARGPPARDPPARATHRATHRB | |
| SCHEMBL29248122 | 0.72 | HTR1A (0.58) | DRD2HTR1AHTR2AHTR7HTR2B | |
| SCHEMBL27482997 | 0.72 | CYP3A4 (0.37) | DRD2MAOBDRD3 | |
| SCHEMBL27333181 | 0.72 | KDM4E (0.33) | — | |
| SCHEMBL27484641 | 0.72 | MMP12 (0.46) | — | |
| SCHEMBL27663613 | 0.72 | CYP19A1 (0.38) | — | |
| SCHEMBL27621246 | 0.71 | PARP1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026945-A | Synthetic method of brimesalamine | 武汉工程大学 | 2024-05-14 | — | — | CN | disclosed |