Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL29248942 | 0.83 | RNASEH1 (0.37) | ALDH1A1SMN1; SMN2KDM4EHPGDKDM5A | |
| SCHEMBL24257810 | 0.81 | RNASEH1 (0.40) | ALDH1A1SMN1; SMN2KDM4EHPGDKDM5A | |
| SCHEMBL30454412 | 0.81 | RNASEH1 (0.40) | ALDH1A1SMN1; SMN2KDM4EHPGDKDM5A | |
| Glycine SCHEMBL30546853 | 0.75 | TDP1 (0.39) | ALDH1A1SMN1; SMN2KDM4EGAATDP1 | |
| SCHEMBL24257827 | 0.73 | RNASEH1 (0.47) | ALDH1A1SMN1; SMN2KDM4EHPGDGAA | |
| SCHEMBL30452343 | 0.73 | RNASEH1 (0.47) | ALDH1A1SMN1; SMN2KDM4EHPGDGAA | |
| SCHEMBL24257456 | 0.70 | EGLN1 (0.48) | — | |
| SCHEMBL24257784 | 0.69 | PPID (0.43) | ALDH1A1KDM4EHPGDGAATDP1 | |
| SCHEMBL30452335 | 0.69 | PPID (0.43) | ALDH1A1KDM4EHPGDGAATDP1 | |
| SCHEMBL23043892 | 0.69 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670131-A | PHD inhibitor compounds, compositions, and methods of use | 阿克比治疗有限公司 | 2023-08-29 | — | — | CN | disclosed |