SCHEMBL29249207

SCHEMBL29249207

Oc1ccc(Oc2ccc(C(F)(C(F)F)C(F)(F)F)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.50
ESR2 Q92731 3/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
LTA4H P09960 6/20 0.44
NR1H2 P55055 1/20 0.44
BAX Q07812 1/20 0.44
KIF11 P52732 1/20 0.38
PARP10 Q53GL7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1719753 0.89 ESR1 (0.54) ESR1ESR2MEN1KMT2ANR1H2
SCHEMBL28512548 0.87 ESR1 (0.52) ESR1ESR2MEN1KMT2AKIF11
SCHEMBL8355667 0.82 ALDH1A1 (0.52) MEN1KMT2AKIF11PARP10
SCHEMBL19328248 0.80 ALDH1A1 (0.49) KMT2APARP10
SCHEMBL7647444 0.78 ESR1 (0.35) ESR1ESR2NR1H2
SCHEMBL27878898 0.77 ESR1 (0.50) ESR1ESR2MEN1KMT2AKIF11
SCHEMBL8999933 0.77 ESR1 (0.75) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL8541423 0.77 NR4A1 (0.53) MEN1KMT2A
SCHEMBL4890621 0.77 POLB (0.51) MEN1KMT2A
SCHEMBL1765673 0.77 KIF11 (0.64) ESR1ESR2MEN1KMT2ALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115044040-B Polyimide-containing polymer, positive photosensitive resin composition, negative photosensitive resin composition, and pattern forming method 信越化学工业株式会社 2024-07-02 CN disclosed
CN-115044040-A Polyimide-containing polymer, positive photosensitive resin composition, negative photosensitive resin composition, and pattern formation method 信越化学工业株式会社 2022-09-13 CN disclosed