SCHEMBL8355667

SCHEMBL8355667

Nc1ccc(Oc2ccc(C(F)(C(F)F)C(F)(F)F)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
MAPT P10636 5/20 0.52
NPC1 O15118 3/20 0.52
RAB9A P51151 3/20 0.52
MAPK1 P28482 2/20 0.52
HPGD P15428 1/20 0.52
TDP1 Q9NUW8 2/20 0.50
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.50
MAOA P21397 2/20 0.44
MAOB P27338 3/20 0.42
TEAD4 Q15561 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41
MITF O75030 1/20 0.41
GAA P10253 1/20 0.41
GFER P55789 1/20 0.41
NLRP1 Q9C000 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL323077 0.89 KIF11 (0.46) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL8364553 0.84 ALDH1A1 (0.54) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL8362662 0.84 MAOB (0.53) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL16338898 0.84 ALDH1A1 (0.41) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL8541423 0.83 NR4A1 (0.53) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL27940217 0.83 L3MBTL1 (0.50) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL29249207 0.82 ESR1 (0.50) MEN1KMT2AKIF11PARP10
SCHEMBL28956109 0.82 NCOA1 (0.38) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL8405668 0.81 ALDH1A1 (0.41) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL21496116 0.81 RAB9A (0.42) ALDH1A1MAPTNPC1RAB9AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116490541-A Optical film having improved optical properties, display device including the same, and method of manufacturing the same 可隆工业株式会社 2023-07-25 CN claimed
CN-107428962-B Polyamide-imide precursor, polyamide-imide film, and display device comprising same 可隆工业株式会社 2021-04-02 CN claimed
CN-107250213-B Polyamide-imide precursor, polyamide-imide film, and display device comprising same 可隆工业株式会社 2020-08-07 CN claimed
CN-111082075-A Preparation method of transition metal, nitrogen and boron co-doped nano composite electrocatalyst 厦门大学 2020-04-28 CN claimed
US-5698135-A POLYAMIC ACID OBTAINED FROM REACTION OF DIANHYDRIDE OF SPECIFIED TETRACARBOXYLIC ACID AND OF CYCLOBUTANETETRACARBOXYLIC ACID WITH DIAMINE, OR POLYMER OBTAINED BY IMIDIZING SAID POLYAMIC ACID JAPAN SYNTHETIC RUBBER CO., LTD., A JAPANESE CORPORATION (JP) 1997-12-16 US claimed
US-5670609-A FILMS WITH LIQUID CCRYSTAL STRUCTURE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-09-23 US claimed
CN-118103210-A Laminate for display device and display device 大日本印刷株式会社 2024-05-28 CN disclosed
CN-117279781-A Laminate for display device and display device 大日本印刷株式会社 2023-12-22 CN disclosed
CN-117099148-A Laminate for display device and display device 大日本印刷株式会社 2023-11-21 CN disclosed
CN-116917126-A Laminate for display device and display device 大日本印刷株式会社 2023-10-20 CN disclosed
CN-114423607-B Front panel for display device, flexible organic electroluminescent display device, laminate for display device, and laminate 大日本印刷株式会社 2023-08-01 CN disclosed
CN-116507595-A Laminate and display device 大日本印刷株式会社 2023-07-28 CN disclosed
CN-116490541-A Optical film having improved optical properties, display device including the same, and method of manufacturing the same 可隆工业株式会社 2023-07-25 CN disclosed
US-5502143-A BLOCK POLYMERS PI MATERIAL RESEARCH LABORATORY (JP) 1996-03-26 US disclosed
US-5502156-A HEAT RESISTANT TIN OXIDE POLYIMIDES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1996-03-26 US disclosed
EP-0486899-B1 Polyimide resin and preparation thereof GRACE W R & CO (US) 1996-01-24 EP disclosed
WO-1995015512-A1 POLY(2,6-PIPERAZINEDIONE) ALIGNMENT LAYER FOR LIQUID CRYSTAL DISPLAYS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-06-08 WO disclosed
EP-0486899-A1 Polyimide resin and preparation thereof W.R. Grace & Co.-Conn. (US) 1992-05-27 EP disclosed
EP-0317941-A2 Photosensitive polyimide polymer compositions HOECHST CELANESE CORPORATION (US) 1989-05-31 EP disclosed
US-4803147-A Photosensitive polyimide polymer compositions HOECHST CELANESE CORPORATION (US) 1989-02-07 US disclosed