SCHEMBL29249784

SCHEMBL29249784

C=CC(=O)N(C)c1ccccc1C#Cc1cccnc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 3/20 0.42
CHRNA4 P43681 3/20 0.42
CYP2A6 P11509 4/20 0.41
FFAR1 O14842 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.38
PTGES O14684 1/20 0.38
GRM5 P41594 3/20 0.37
ERN1 O75460 1/20 0.37
CSF1R P07333 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2B6 P20813 1/20 0.36
CYP2C19 P33261 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31092720 1.00 CHRNB2 (0.42) CHRNB2CHRNA4CYP2A6FFAR1PTGDR2
SCHEMBL29249809 0.86 NPC1 (0.43) FFAR1CYP2C9CYP2C19CYP1A2
SCHEMBL29249786 0.80 CA12 (0.43) FFAR1
SCHEMBL29249785 0.79 PTGDR2 (0.42) PTGDR2PTGESGRM5CYP2C9
SCHEMBL29249801 0.79 LMNA (0.43) FFAR1
SCHEMBL29249778 0.79 APP (0.37) FFAR1
SCHEMBL29249865 0.77 BCL2A1 (0.41) FFAR1PTGDR2GRM5
SCHEMBL29249830 0.77 BCL2A1 (0.46) FFAR1PTGES
SCHEMBL29249803 0.77 ACACB (0.38) FFAR1
SCHEMBL29249832 0.77 MEN1 (0.35) CYP2A6GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324695-A Method for selectively preparing quinoline-2-ketone or 3, 4-dihydro-quinoline-2-ketone compound under regulation of photocatalyst 浙江工业大学 2024-07-12 CN disclosed