Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30584601 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TDP1HPGDMEN1KMT2A | |
| SCHEMBL21358342 | 0.79 | PIN1 (0.57) | ALDH1A1TDP1HPGDKMT2ACHRNB2 | |
| SCHEMBL29538390 | 0.76 | MAPT (0.42) | ALDH1A1TDP1HPGDMEN1KMT2A | |
| SCHEMBL23243706 | 0.75 | ABCG2 (0.49) | ALDH1A1TDP1HPGDKMT2ACHRNB2 | |
| SCHEMBL11453175 | 0.74 | LMNA (0.57) | ALDH1A1TDP1HPGDMEN1KMT2A | |
| SCHEMBL10596737 | 0.74 | MEN1 (0.56) | ALDH1A1TDP1HPGDMEN1KMT2A | |
| SCHEMBL4203388 | 0.73 | TSHR (0.67) | ALDH1A1TDP1MEN1KMT2ACHRNB2 | |
| SCHEMBL28140787 | 0.72 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ACHRNB2CHRNA4 | |
| SCHEMBL30043252 | 0.72 | TSHR (0.64) | ALDH1A1TDP1MEN1KMT2ACHRNB2 | |
| SCHEMBL6273333 | 0.72 | TSHR (0.64) | ALDH1A1TDP1MEN1KMT2ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685583-A | Pyrimidine compounds, compositions and pharmaceutical uses thereof | 缆图药品公司 | 2023-09-01 | — | — | CN | disclosed |