Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28859641 | 0.90 | KCNH2 (0.48) | HSD17B10KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL29251902 | 0.90 | HSD17B10 (0.41) | HSD17B10KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL1551957 | 0.87 | HSD17B10 (0.49) | HSD17B10KCNH2SMN1; SMN2HDAC8ACHE | |
| SCHEMBL29252922 | 0.86 | LMNA (0.41) | HSD17B10KCNH2LMNAHTTSMN1; SMN2 | |
| Fluoride Ion SCHEMBL30331061 | 0.85 | HSD17B10 (0.47) | HSD17B10KCNH2HDAC8ACHE | |
| Hydrochloric Acid SCHEMBL11431543 | 0.85 | HSD17B10 (0.47) | HSD17B10KCNH2HDAC8ACHE | |
| Acetic Acid SCHEMBL29252315 | 0.83 | HSD17B10 (0.41) | HSD17B10HDAC8 | |
| SCHEMBL30212748 | 0.82 | HSD17B10 (0.45) | HSD17B10KCNH2HDAC8ACHE | |
| SCHEMBL16699569 | 0.81 | KCNH2 (0.36) | KCNH2CA1CA2CA9ACHE | |
| SCHEMBL29251628 | 0.81 | KCNH2 (0.36) | KCNH2CA1CA2CA9ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999475-A | Electrochemical gas sensor and electrolyte for electrochemical gas sensor | 德尔格安全股份两合公司 | 2024-05-07 | — | — | CN | disclosed |