SCHEMBL29252574

SCHEMBL29252574

CCCCC1CCN(CCCC)CC1.CS(=O)(=O)O

nearest known ligand 0.50

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 4/20 0.50
DRD2 known ✓ P14416 3/20 0.50
DRD4 known ✓ P21917 3/20 0.50
ADRA1D known ✓ P25100 2/20 0.50
ADRA1A known ✓ P35348 2/20 0.50
ADRA1B known ✓ P35368 2/20 0.50
HTR1A known ✓ P08908 1/20 0.50
ADRA2A known ✓ P08913 1/20 0.50
ADRA2B known ✓ P18089 1/20 0.50
DRD3 known ✓ P35462 2/20 0.45
ADRB2 known ✓ P07550 1/20 0.45
CHRM2 P08172 3/20 0.50
CHRM4 P08173 3/20 0.50
CHRM5 P08912 3/20 0.50
CHRM3 P20309 3/20 0.50
HRH1 P35367 1/20 0.50
GNAO1 P09471 4/20 0.49
HRH3 Q9Y5N1 1/20 0.47
GNAI3 P08754 3/20 0.46
GNAI1 P63096 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29252746 0.95 GNAO1 (0.55) CHRM1CHRM2CHRM4CHRM5DRD2
SCHEMBL29252608 0.94 GNAO1 (0.57) CHRM1CHRM2CHRM4CHRM5DRD2
SCHEMBL29252136 0.94 GNAO1 (0.57) CHRM1CHRM2CHRM4CHRM5DRD2
SCHEMBL29252351 0.94 GNAO1 (0.57) CHRM1CHRM2CHRM4CHRM5DRD2
SCHEMBL29251672 0.94 GNAO1 (0.57) CHRM1CHRM2CHRM4CHRM5DRD2
SCHEMBL29252011 0.94 GNAO1 (0.57) CHRM1CHRM2CHRM4CHRM5DRD2
SCHEMBL29252021 0.94 GNAO1 (0.57) CHRM1CHRM2CHRM4CHRM5DRD2
SCHEMBL29252366 0.94 GNAO1 (0.57) CHRM1CHRM2CHRM4CHRM5DRD2
SCHEMBL29252899 0.93 GNAO1 (0.49) CHRM1CHRM2CHRM4CHRM5DRD2
SCHEMBL29252643 0.93 CHRM1 (0.47) CHRM1CHRM2CHRM4CHRM5DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117999475-A Electrochemical gas sensor and electrolyte for electrochemical gas sensor 德尔格安全股份两合公司 2024-05-07 CN disclosed