Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 9/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.48 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.41 |
| ▸ | MICA | Q29983 | 2/20 | 0.41 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.41 |
| ▸ | MTTP | P55157 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | APOB | P04114 | 3/20 | 0.39 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925288 | 0.89 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL3415834 | 0.89 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL2930629 | 0.89 | RORB (0.46) | HCRTR1HCRTR2KLRK1MICARAET1L | |
| SCHEMBL2930541 | 0.88 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL3415643 | 0.88 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL2924532 | 0.86 | SLC6A4 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL3417003 | 0.86 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL2931897 | 0.86 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL2931380 | 0.84 | HCRTR1 (0.46) | HCRTR1HCRTR2KLRK1MICARAET1L | |
| SCHEMBL2931080 | 0.83 | HCRTR1 (0.42) | HCRTR1HCRTR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079690-B1 | 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-09-15 | — | — | EP | disclosed |