Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 2/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10167513 | 0.89 | KCNA5 (0.42) | KCNA5RAD52MEN1KMT2ALMNA | |
| SCHEMBL10167516 | 0.86 | KCNA5 (0.41) | KCNA5RAD52MEN1KMT2ATP53 | |
| SCHEMBL10167489 | 0.85 | HCRTR1 (0.38) | MEN1KMT2ATP53LMNAADORA2A | |
| SCHEMBL10167509 | 0.85 | RAD52 (0.51) | KCNA5RAD52MEN1KMT2ATP53 | |
| SCHEMBL10167510 | 0.84 | MAPT (0.43) | KCNA5RAD52MEN1KMT2ATP53 | |
| SCHEMBL10167444 | 0.83 | KCNA5 (0.40) | KCNA5DYRK1ATP53LMNAADORA2A | |
| SCHEMBL10167434 | 0.82 | ALDH1A1 (0.37) | MEN1KMT2ATP53LMNAADORA2A | |
| SCHEMBL13903749 | 0.81 | KCNA5 (0.45) | KCNA5RAD52MEN1KMT2ATP53 | |
| SCHEMBL13903768 | 0.80 | KCNA5 (0.44) | KCNA5RAD52MEN1KMT2ATP53 | |
| SCHEMBL10167501 | 0.80 | KCNA5 (0.40) | KCNA5RAD52MEN1KMT2ADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |
| US-8119568-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest II | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119568-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest II | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119568-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest II | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BASF SE (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BASF SE (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BASF SE (DE) | 2010-01-14 | — | — | US | disclosed |
| EP-2064196-A2 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF Aktiengesellschaft (DE) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008090048-A2 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2008-07-31 | — | — | WO | disclosed |
| WO-2008090048-A2 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2008-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BPNT1, BCAT1, TGFBR1 | KCNA5 1882/4885RAD52 1818/4885MEN1 3020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.