Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.42 |
| ▸ | LTA4H | P09960 | 7/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31086398 | 1.00 | RXRA (0.42) | RXRAGRIN1GRIN2BLTA4HKCNH2 | |
| SCHEMBL29255165 | 0.91 | RXRA (0.44) | RXRAGRIN1GRIN2B | |
| SCHEMBL31086352 | 0.91 | RXRA (0.44) | RXRAGRIN1GRIN2B | |
| SCHEMBL29254761 | 0.90 | RXRA (0.39) | RXRAGRIN1GRIN2BLTA4HKCNH2 | |
| SCHEMBL31086301 | 0.90 | RXRA (0.39) | RXRAGRIN1GRIN2BLTA4HKCNH2 | |
| SCHEMBL31086476 | 0.85 | DRD2 (0.42) | LTA4HKCNH2CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL29254780 | 0.85 | DRD2 (0.42) | LTA4HKCNH2CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL31086415 | 0.85 | LTA4H (0.44) | RXRAGRIN1GRIN2BLTA4HKCNH2 | |
| SCHEMBL29254980 | 0.85 | LTA4H (0.44) | RXRAGRIN1GRIN2BLTA4HKCNH2 | |
| SCHEMBL31086351 | 0.84 | LTA4H (0.51) | RXRAGRIN1GRIN2BLTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307534-A | LTA4H inhibitors and uses thereof | 上海海雁医药科技有限公司 | 2024-07-09 | — | — | CN | disclosed |