Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.62 |
| ▸ | HTR2B | P41595 | 2/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | ACP3 | P15309 | 2/20 | 0.51 |
| ▸ | MIF | P14174 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2647553 | 0.80 | HTR2A (0.54) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL3237564 | 0.79 | TAAR1 (0.64) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL5103155 | 0.79 | TAAR1 (0.64) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL2659237 | 0.78 | HTR2A (0.77) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL19040919 | 0.78 | HTR2A (0.71) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| Hydrochloric Acid SCHEMBL31537553 | 0.78 | BDKRB2 (0.55) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| Hydrochloric Acid SCHEMBL625289 | 0.78 | BDKRB2 (0.55) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| Bromide SCHEMBL27753357 | 0.78 | TAAR1 (0.58) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| Bromide SCHEMBL3602081 | 0.78 | TAAR1 (0.58) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| Nordexfenfluramine SCHEMBL895637 | 0.77 | HTR2A (1.00) | HTR2AHTR2BHTR2CTAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307592-A | Quaternary phosphate compound and preparation method thereof | 北京大学 | 2024-07-09 | — | — | CN | disclosed |