Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 known ✓ | P30411 | 6/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31537553 | 1.00 | BDKRB2 (0.55) | BDKRB2HTR2AHTR2BHTR2CSIGMAR1 | |
| SCHEMBL28260251 | 0.79 | TAAR1 (0.59) | HTR2AHTR2BHTR2CSIGMAR1LMNA | |
| SCHEMBL28261580 | 0.79 | TAAR1 (0.59) | HTR2AHTR2BHTR2CSIGMAR1LMNA | |
| SCHEMBL2094737 | 0.79 | TAAR1 (0.59) | HTR2AHTR2BHTR2CSIGMAR1LMNA | |
| SCHEMBL28143319 | 0.79 | TAAR1 (0.59) | HTR2AHTR2BHTR2CSIGMAR1LMNA | |
| Bromide SCHEMBL29255353 | 0.78 | HTR2A (0.62) | HTR2AHTR2BHTR2CSIGMAR1LMNA | |
| SCHEMBL7929109 | 0.77 | TAAR1 (0.61) | HTR2AHTR2BHTR2CSIGMAR1LMNA | |
| SCHEMBL28853147 | 0.77 | HTR2A (0.62) | HTR2AHTR2BHTR2CSIGMAR1LMNA | |
| Hydrochloric Acid SCHEMBL28445004 | 0.76 | BDKRB2 (0.70) | BDKRB2TP53 | |
| Hydrochloric Acid SCHEMBL5088466 | 0.76 | BDKRB2 (0.70) | BDKRB2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005524748-A | — | — | 2005-08-18 | — | — | JP | claimed |
| US-6852417-B2 | Composition for improving adhesion of base-resistant fluoroelastomers to metal, ceramic or glass substrates | DUPONT DOW ELASTOMERS, LLC (US) | 2005-02-08 | — | — | US | claimed |
| EP-1501887-A1 | COMPOSITION FOR IMPROVING ADHESION OF BASE-RESISTANT FLUOROELASTOMERS TO METAL, CERAMIC OR GLASS SUBSTRATES | DUPONT DOW ELASTOMERS L.L.C. (US) | 2005-02-02 | — | — | EP | claimed |
| US-20030225189-A1 | Composition for improving adhesion of base-resistant fluoroelastomers to metal, ceramic or glass substrates | DUPONT DOW ELASTOMERS LLC | 2003-12-04 | — | — | US | claimed |
| WO-2003095535-A1 | COMPOSITION FOR IMPROVING ADHESION OF BASE-RESISTANT FLUOROELASTOMERS TO METAL, CERAMIC OR GLASS SUBSTRATES | DUPONT DOW ELASTOMERS L.L.C. (US) | 2003-11-20 | — | — | WO | claimed |
| US-4758618-A | Curable composition of elastomeric vinylidene fluoride copolymer | ASAHI GLASS COMPANY, LTD. (JP) | 1988-07-19 | — | — | US | claimed |
| US-20260098005-A1 | NON-FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS | THE CHEMOURS COMPANY FC, LLC (US) | 2026-04-09 | — | — | US | disclosed |
| EP-4602105-A1 | CURABLE FLUOROELASTOMER COMPOSITIONS AND LOW-FRICTION CURED FLUOROELASTOMERS (FKM) FORMED THEREFROM | The Chemours Company FC, LLC (US) | 2025-08-20 | — | — | EP | disclosed |
| EP-4590762-A1 | FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS | The Chemours Company FC, LLC (US) | 2025-07-30 | — | — | EP | disclosed |
| EP-4590761-A1 | NON-FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS | The Chemours Company FC, LLC (US) | 2025-07-30 | — | — | EP | disclosed |
| US-20240239931-A1 | FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS | CHEMOURS COMPANY FC, LLC, THE | 2024-07-18 | — | — | US | disclosed |
| WO-2024081314-A1 | CURABLE FLUOROELASTOMER COMPOSITIONS AND LOW-FRICTION CURED FLUOROELASTOMERS (FKM) FORMED THEREFROM | THE CHEMOURS COMPANY FC, LLC (US) | 2024-04-18 | — | — | WO | disclosed |
| WO-2024064108-A1 | NON-FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS | THE CHEMOURS COMPANY FC, LLC (US) | 2024-03-28 | — | — | WO | disclosed |
| US-4758618-A | Curable composition of elastomeric vinylidene fluoride copolymer | ASAHI GLASS COMPANY, LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| EP-0218929-A2 | Curable composition of elastomeric vinylidene fluoride copolymer | ASAHI GLASS COMPANY LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| EP-0127318-B1 | CURABLE FLUOROPOLYMER COMPOSITION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-04-01 | — | — | EP | disclosed |
| EP-0140207-A2 | A process for rapidly curing a brominated fluoroelastomer | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-05-08 | — | — | EP | disclosed |
| US-4496682-A | TWO-STAGE CURING WITH BISPHENOLS, BISAMINES, QUATERNARY AMMONIUM OR PHOSPHONIUM COMPONENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-01-29 | — | — | US | disclosed |
| US-4489196-A | CONTAINING VULCANIZATION ACCELERATOR, CROSSLINKING AGENT, METAL OXIDE OR HYDROXIDE, AND POLYOL COACCELERATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-18 | — | — | US | disclosed |
| EP-0127484-A2 | Curable fluoropolymer containing aromatic amine | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260098005-A1 | NON-FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS | CBR1, NAF1, CBR3 | BDKRB2 2640/4885HTR2A 3046/4885HTR2B 3719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.