Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30205665 | 1.00 | PTPN1 (0.59) | PTPN1HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL1122641 | 0.86 | PTPN1 (0.77) | PTPN1RAB9ACTSSCTSKGAA | |
| SCHEMBL4362292 | 0.84 | CTSL (0.53) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8339427 | 0.84 | ROCK2 (0.65) | RAB9AGAAGPR132ALDH1A1MAPT | |
| SCHEMBL4363867 | 0.82 | GAA (0.53) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1123055 | 0.82 | GAA (0.80) | PTPN1RAB9AGAAGPR132MMP9 | |
| SCHEMBL4367288 | 0.81 | CTSL (0.58) | PTPN1RAB9ACTSSCTSKCA2 | |
| SCHEMBL4372161 | 0.81 | CTSL (0.61) | PTPN1RAB9ACTSSCTSKNPC1 | |
| SCHEMBL30074931 | 0.81 | ITGB3 (0.52) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27933195 | 0.81 | ITGB3 (0.52) | HDAC8HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650875-A | Dichondra repens element derivative and preparation method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-01-31 | — | — | CN | claimed |
| CN-115650875-B | Zantedeschia aethiopica derivative and preparation method and application thereof | 贵州省天然产物研究中心 | 2024-05-14 | — | — | CN | disclosed |
| CN-115650875-A | Dichondra repens element derivative and preparation method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-01-31 | — | — | CN | disclosed |