Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | CDK14 | O94921 | 7/20 | 0.40 |
| ▸ | CCNY | Q8ND76 | 7/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29256739 | 0.89 | CDK14 (0.42) | DRD2CCNT1CDK9CDK5CDK5R1 | |
| SCHEMBL22582168 | 0.85 | CDK14 (0.43) | CCNT1CDK9CDK5CDK5R1CDK14 | |
| SCHEMBL31664698 | 0.84 | CDK9 (0.44) | CCNT1CDK9CDK5CDK5R1CDK14 | |
| SCHEMBL26123683 | 0.84 | CDK9 (0.44) | CCNT1CDK9CDK5CDK5R1CDK14 | |
| SCHEMBL30689623 | 0.84 | CDK9 (0.44) | CCNT1CDK9CDK5CDK5R1CDK14 | |
| SCHEMBL30689600 | 0.84 | CDK9 (0.44) | CCNT1CDK9CDK5CDK5R1CDK14 | |
| SCHEMBL30689624 | 0.83 | CDK5 (0.45) | CCNT1CDK9CDK5CDK5R1CDK14 | |
| SCHEMBL8212911 | 0.83 | CCNT1 (0.48) | DRD2DRD3CCNT1CDK9CDK5 | |
| SCHEMBL959324 | 0.82 | CNR1 (0.49) | CCNT1CDK9CDK5CDK5R1CDK14 | |
| SCHEMBL8262979 | 0.82 | CDK5 (0.48) | CCNT1CDK9CDK5CDK5R1CDK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221645-A | Proteolysis targeting chimeric and preparation method, pharmaceutical composition and application thereof | 河北康泰药业有限公司 | 2024-06-21 | — | — | CN | disclosed |