Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 5/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.44 |
| ▸ | CDK14 | O94921 | 11/20 | 0.42 |
| ▸ | CCNY | Q8ND76 | 11/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CASK | O14936 | 1/20 | 0.41 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | MAK | P20794 | 1/20 | 0.41 |
| ▸ | CDK11B | P21127 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31664698 | 1.00 | CDK9 (0.44) | CDK9CDK5CCNT1CDK5R1CDK14 | |
| SCHEMBL30689600 | 1.00 | CDK9 (0.44) | CDK9CDK5CCNT1CDK5R1CDK14 | |
| SCHEMBL30689623 | 1.00 | CDK9 (0.44) | CDK9CDK5CCNT1CDK5R1CDK14 | |
| SCHEMBL30689624 | 0.99 | CDK5 (0.45) | CDK9CDK5CCNT1CDK5R1CDK14 | |
| SCHEMBL30689622 | 0.93 | CDK5 (0.47) | CDK9CDK5CCNT1CDK5R1CDK14 | |
| SCHEMBL8262979 | 0.86 | CDK5 (0.48) | CDK9CDK5CCNT1CDK5R1CDK14 | |
| SCHEMBL8212911 | 0.85 | CCNT1 (0.48) | CDK9CDK5CCNT1CDK5R1CDK14 | |
| SCHEMBL29256732 | 0.84 | DRD2 (0.53) | CDK9CDK5CCNT1CDK5R1CDK14 | |
| SCHEMBL24757744 | 0.84 | CDK14 (0.49) | CDK9CDK5CCNT1CDK5R1CDK14 | |
| SCHEMBL8262582 | 0.83 | CDK5 (0.46) | CDK9CDK5CCNT1CDK5R1CDK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250236607-A1 | CYCLIN-DEPENDENT KINASE 9 (CDK9) DEGRADERS AND METHODS OF USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2025-07-24 | — | — | US | disclosed |
| EP-4499148-A1 | CYCLIN-DEPENDENT KINASE 9 (CDK9) DEGRADERS AND METHODS OF USING THEREOF | Ohio State Innovation Foundation (US) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023192534-A1 | CYCLIN-DEPENDENT KINASE 9 (CDK9) DEGRADERS AND METHODS OF USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2023-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250236607-A1 | CYCLIN-DEPENDENT KINASE 9 (CDK9) DEGRADERS AND METHODS OF USING THEREOF | CDK9, CDK19, CDKL2 | CDK9 1/4885CDK5 20/4885CCNT1 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.