Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | KDM5A | P29375 | 2/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28665862 | 0.83 | DNM1 (0.46) | DNM1TSHRTHRBGGPS1CA12 | |
| SCHEMBL28403203 | 0.83 | DNM1 (0.46) | DNM1TSHRTHRBGGPS1CA12 | |
| Hydrochloric Acid SCHEMBL22263437 | 0.77 | DNM1 (0.42) | DNM1TSHRTHRBGGPS1 | |
| Hydrochloric Acid SCHEMBL22263500 | 0.77 | DNM1 (0.42) | DNM1TSHRTHRBGGPS1 | |
| SCHEMBL8499586 | 0.76 | DNM1 (0.39) | DNM1TSHRGGPS1CA12CA1 | |
| Hydrochloric Acid SCHEMBL22263449 | 0.73 | DNM1 (0.42) | DNM1TSHRTHRBGGPS1 | |
| Bromide SCHEMBL30528224 | 0.71 | DNM1 (0.46) | DNM1TSHRTHRBGGPS1CA12 | |
| Bromide SCHEMBL31249480 | 0.71 | DNM1 (0.46) | DNM1TSHRTHRBGGPS1CA12 | |
| Bromide SCHEMBL11339984 | 0.71 | DNM1 (0.63) | DNM1KCNH2KDM5APHF8KDM4C | |
| SCHEMBL10884812 | 0.71 | DNM1 (0.58) | DNM1KCNH2KDM5APHF8KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118329582-A | Method for visually detecting trace lead ions in mixed acid system nickel electrolyte | 中国科学院兰州化学物理研究所 | 2024-07-12 | — | — | CN | disclosed |