Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954478 | 0.94 | ALDH1A1 (0.39) | DNM1ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL10949520 | 0.87 | ALDH1A1 (0.40) | ALDH1A1CA12CA1CA9FDPS | |
| SCHEMBL28665862 | 0.87 | DNM1 (0.46) | DNM1TSHRGGPS1CA12CA1 | |
| SCHEMBL28403203 | 0.87 | DNM1 (0.46) | DNM1TSHRGGPS1CA12CA1 | |
| SCHEMBL9463571 | 0.86 | LMNA (0.41) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL28939280 | 0.83 | SMN1; SMN2 (0.44) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL22263437 | 0.80 | DNM1 (0.42) | DNM1TSHRGGPS1FDPS | |
| Hydrochloric Acid SCHEMBL22263500 | 0.80 | DNM1 (0.42) | DNM1TSHRGGPS1FDPS | |
| SCHEMBL8499163 | 0.78 | LMNA (0.40) | DNM1ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL8498056 | 0.78 | LMNA (0.40) | DNM1ALDH1A1LMNAHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |