SCHEMBL28403203

SCHEMBL28403203

CCCCCCCCCCCCN(CCCCCCCCCCCC)C(CCCCCCCCCCC)(CCCCCCCCCCCC)CCCCCCCCCCCC

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.46
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
GGPS1 O95749 5/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
FDPS P14324 7/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28665862 1.00 DNM1 (0.46) DNM1TSHRTHRBGGPS1CA12
Hydrochloric Acid SCHEMBL22263437 0.93 DNM1 (0.42) DNM1TSHRTHRBGGPS1FDPS
Hydrochloric Acid SCHEMBL22263500 0.93 DNM1 (0.42) DNM1TSHRTHRBGGPS1FDPS
Hydrochloric Acid SCHEMBL22263449 0.88 DNM1 (0.42) DNM1TSHRTHRBGGPS1FDPS
SCHEMBL8499586 0.87 DNM1 (0.39) DNM1TSHRGGPS1CA12CA1
Bromide SCHEMBL29256751 0.83 DNM1 (0.40) DNM1TSHRTHRBGGPS1CA12
SCHEMBL29723530 0.82 DNM1 (0.50) DNM1TSHRGGPS1FDPS
Hydrochloric Acid SCHEMBL22263433 0.80 TSHR (0.40) DNM1TSHRTHRBGGPS1FDPS
SCHEMBL6897518 0.80 DNM1 (0.46) DNM1TSHRTHRBGGPS1CA12
SCHEMBL4954478 0.79 ALDH1A1 (0.39) DNM1TSHRGGPS1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111454165-A Novel lipid and lipid nanoparticle formulations for delivery of nucleic acids 爱康泰生治疗公司 2020-07-28 CN disclosed
CN-106795096-B Novel lipid and lipid nanoparticle formulations for delivery of nucleic acids 爱康泰生治疗公司 2020-05-29 CN disclosed