SCHEMBL29257

SCHEMBL29257

O=C(O)Cc1ccc(Br)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.71
KMT2A Q03164 1/20 0.71
SRD5A2 P31213 1/20 0.65
CA2 P00918 1/20 0.62
CAMK2A Q9UQM7 1/20 0.62
AKR1B1 P15121 1/20 0.61
LMNA P02545 2/20 0.58
GAA P10253 2/20 0.58
TSHR P16473 2/20 0.58
ABCC4 O15439 1/20 0.58
PTGS1 P23219 1/20 0.58
HTT P42858 1/20 0.58
PPARD Q03181 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.53
HPGD P15428 3/20 0.52
ALDH1A1 P00352 2/20 0.52
HSD17B10 Q99714 2/20 0.52
FFAR1 O14842 1/20 0.52
POLB P06746 2/20 0.50
NSD2 O96028 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3787817 0.98 MEN1 (0.69) MEN1KMT2ASRD5A2CA2CAMK2A
Methane SCHEMBL27567373 0.98 MEN1 (0.69) MEN1KMT2ASRD5A2CA2CAMK2A
Hydrochloric Acid SCHEMBL2530497 0.98 MEN1 (0.69) MEN1KMT2ASRD5A2CA2CAMK2A
SCHEMBL8173807 0.93 ABCC4 (0.69) MEN1KMT2ASRD5A2CA2CAMK2A
SCHEMBL6253799 0.89 MEN1 (0.61) MEN1KMT2ASRD5A2CA2CAMK2A
SCHEMBL5153004 0.89 MEN1 (0.61) MEN1KMT2ASRD5A2CA2CAMK2A
Felbinac SCHEMBL6896878 0.88 LMNA (0.81) MEN1KMT2ASRD5A2CA2CAMK2A
SCHEMBL69614 0.87 CA2 (0.79) MEN1KMT2ACA2CAMK2AAKR1B1
Hydrochloric Acid SCHEMBL25180348 0.84 CA2 (0.75) MEN1KMT2ASRD5A2CA2CAMK2A
Hydrochloric Acid SCHEMBL6765874 0.84 CA2 (0.75) MEN1KMT2ASRD5A2CA2CAMK2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3088 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-120118025-A Preparation and multifunctional therapeutic application of D-A configuration single-molecule graphene quantum dot 武汉科技大学 2025-06-10 CN claimed
CN-119859135-A Rayleigh Lu Geli intermediate and preparation method thereof 浙江工业大学 2025-04-22 CN claimed
CN-119841727-A Method for directly preparing carboxylic ester compound from aromatic aldehyde, ketone and carboxylic acid 湖南第一师范学院 2025-04-18 CN claimed
CN-119409624-A In nilaparib Process for the preparation of intermediates 泰迩生物医药泰州有限公司 2025-02-11 CN claimed
CN-118598771-A Oral small molecule P-selectin inhibitor, and preparation method and application thereof 首都医科大学 2024-09-06 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-118359500-A Single-layer water-soluble graphene quantum dot and preparation method and application thereof 武汉科技大学 2024-07-19 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
US-20240182421-A1 SYNTHESIS OF ENDOCHIN-LIKE QUINOLONES OREGON HEALTH & SCIENCE UNIVERSITY (US) 2024-06-06 US claimed
EP-0818562-A1 Composition for treating copper and copper alloy surfaces and method for the surface treatment MEC CO., Ltd. (JP) 1998-01-14 EP claimed
EP-0701558-A1 PROCESS OF MAKING SPIROCYCLES AND ANALOGS THEREOF MERCK & CO. INC. (US) 1996-03-20 EP claimed
US-5496590-A Composition for treating copper and copper alloy surfaces and method for the surface treatment MEC CO., LTD. (JP) 1996-03-05 US claimed
EP-0643154-A2 Composition for treating copper and copper alloy surfaces and method for the surface treatment MEC CO., Ltd. (JP) 1995-03-15 EP claimed
WO-1994029317-A1 PROCESS OF MAKING SPIROCYCLES AND ANALOGS THEREOF MERCK & CO., INC. (US) 1994-12-22 WO claimed
US-5137981-A Heat resistant rubber; esterification butadiene polymer using halogenated carboxy compound BRIDGESTONE CORPORATION (JP) 1992-08-11 US claimed
EP-0328291-B1 HALOGENATED POLYBUTADIENE SERIES ELASTOMERS, METHOD OF PRODUCING THE SAME, AND RUBBER COMPOSITIONS FOR TIRES CONTAINING THE ELASTOMER Bridgestone Corporation (JP) 1992-04-29 EP claimed
EP-0263022-B1 MESOMORPHIC POLYMERS CONTAINING SIDE CHAINS, DERIVED FROM 1-(PHENYL)-2-(4-CYANOPHENYL) ETHANE THOMSON-CSF (FR) 1990-11-07 EP claimed
EP-0328291-A1 Halogenated polybutadiene series elastomers, method of producing the same, and rubber compositions for tires containing the elastomer Bridgestone Corporation (JP) 1989-08-16 EP claimed
EP-0157679-B1 ORGANIC COMPOUND SHOWING A SMECTIC PHASE A, MIXTURE CONTAINING THIS COMPOUND AND PROCESS FOR MAKING IT THOMSON-CSF (FR) 1988-05-18 EP claimed