Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481866 | 0.95 | ENPEP (0.43) | LMNAALDH1A1THRBTP53ENPEP | |
| Lithium Ion SCHEMBL29257535 | 0.86 | ENPEP (0.42) | LMNAALDH1A1THRBTP53ENPEP | |
| SCHEMBL29257532 | 0.82 | ENPEP (0.47) | LMNAALDH1A1THRBTP53ENPEP | |
| Glycerin SCHEMBL29119754 | 0.76 | TP53 (0.58) | LMNAALDH1A1THRBTP53TSHR | |
| Glycerin SCHEMBL3358540 | 0.76 | TP53 (0.58) | LMNAALDH1A1THRBTP53TSHR | |
| Glycerin SCHEMBL1712543 | 0.76 | TP53 (0.58) | LMNAALDH1A1THRBTP53ENPEP | |
| Glycerin SCHEMBL29119760 | 0.76 | TP53 (0.58) | LMNAALDH1A1THRBTP53TSHR | |
| Glycerin SCHEMBL1712541 | 0.76 | TP53 (0.58) | LMNAALDH1A1THRBTP53ENPEP | |
| Glycerin SCHEMBL2856963 | 0.76 | TP53 (0.58) | LMNAALDH1A1THRBTP53TSHR | |
| Glycerin SCHEMBL11173648 | 0.76 | TP53 (0.58) | LMNAALDH1A1THRBTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146124-A | Sulfonate containing ester group, preparation process and application thereof | 苏州祺添新材料股份有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-118146124-A | Sulfonate containing ester group, preparation process and application thereof | 苏州祺添新材料股份有限公司 | 2024-06-07 | — | — | CN | disclosed |